منابع مشابه
Specific nucleoprotein residues affect influenza virus morphology.
Influenza virus strains are often pleiomorphic, a characteristic that is largely attributed to specific residues in matrix protein 1 (M1). Although the mechanism by which M1 controls virion morphology has not yet been defined, it is suggested that the M1 interaction with other viral proteins plays an important role. In this study, we rescued recombinant virus WSN-AichiM1 containing the spherica...
متن کاملVirus morphology as an aid for rapid diagnosis.
Standard methods of virus diagnosis may take many days to complete. As antiviral drugs are being used with more effectiveness, it becomes more important to develop rapid diagnostic methods. It takes only a few minutes to prepare and examine a specimen for electron microscopy (EM), using the negative staining technique. Viruses in the specimen can readily be identified by their morphology. In or...
متن کاملMorphology of deoxyribonucleic acid extracted from cores of vaccinia virus.
It has become apparent during the past few years that viral genomes may exist, at some stage of their life cycle, as an endless structure that can for convenience be termed a circle. The deoxyribonucleic acid (DNA) of small viruses such as polyoma appears to exist in this form inside the virion, since it can be extracted as rings a few microns in length (R. Weil and J. Vinograd, Proc. Natl. Aca...
متن کاملMorphology of the nucleoprotein component of rabies virus.
The intracytoplasmic ground substance, or matrix, associated with the development of rabies virus and the nucleocapsid of the virus were investigated. The filaments of the matrix were identified as virus-specific by means of ferritin-labeled antibodies. In thin sections, the diameter was 15 nm and the strands seemed to be incorporated into virions during morphogenesis of the virus. The nucleoca...
متن کاملMultiple effects of an anti-human immunodeficiency virus nucleocapsid inhibitor on virus morphology and replication.
Human immunodeficiency virus type 1 nucleocapsid protein is a major structural component of the virion core and a key factor involved in proviral DNA synthesis and virus formation. 2,2'-Dithiobenzamides (DIBA-1) and related compounds that are inhibitors of NCp7 are thought to eject zinc ions from NCp7 zinc fingers, inhibiting the maturation of virion proteins. Here, we show that the presence of...
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ژورنال
عنوان ژورنال: Journal of Hospital Infection
سال: 1989
ISSN: 0195-6701
DOI: 10.1016/0195-6701(89)90144-8